Description : Cytoplasmic thioredoxin isoenzyme; part of thioredoxin system which protects cells against oxidative and reductive stress; forms LMA1 complex with Pbi2p; acts as a cofactor for Tsa1p; required for ER-Golgi transport and vacuole inheritance; with Trx2p, facilitates mitochondrial import of small Tims Tim9p, Tim10p, Tim13p by maintaining them in reduced form; abundance increases iunder DNA replication stress; TRX1 has a paralog, TRX2, that arose from the whole genome duplication [Source:SGD;Acc:S000004033]

Gene families : OG_03_0000156 (OF) Phylogenetic Tree(s): OG0000156_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR: YLR043C
Cluster HCCA: Cluster_67

Target Alias Description ECC score Gene Family Method Actions
AFR97811 No alias thioredoxin;Thioredoxin 0.06 OF
AOA70296 No alias Thioredoxin domain 0.06 OF
CBF80822 No alias thioredoxin, putative 0.06 OF
EAL88880 No alias thioredoxin, putative 0.04 OF
EFI28356 No alias Thioredoxin domain 0.02 OF
EGR51066 No alias Thioredoxin domain 0.03 OF
ESA44307 No alias Thioredoxin domain 0.02 OF
ESU16031 No alias Thioredoxin domain 0.03 OF

Type GO Term Name Evidence Source

No GO annotation available for this sequence

Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR013766 Thioredoxin_domain 5 100
No external refs found!