Description : Protein required for maturation of mitochondrial [4Fe-4S] proteins; functions in a complex with Isa2p and possibly Iba57p; isa1 deletion causes loss of mitochondrial DNA and respiratory deficiency; depletion reduces growth on nonfermentable carbon sources; functional ortholog of bacterial A-type ISC proteins; human ISCA1 can complement isa1 null mutant [Source:SGD;Acc:S000003950]
Gene families : OG_03_0001296 (OF) Phylogenetic Tree(s): OG0001296_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YLL027W | |
Cluster | HCCA: Cluster_7 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AOA65770 | No alias | FeS cluster biogenesis | 0.02 | OF | |
CBF85927 | No alias | iron-sulfur cluster assembly accessory protein Isa1, putative | 0.03 | OF | |
EAU92939 | No alias | iron sulfur assembly protein 1 | 0.03 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No GO annotation available for this sequence |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR000361 | FeS_biogenesis | 147 | 246 |
No external refs found! |