Description : Dynamin-related GTPase involved in mitochondrial organization; required for mitochondrial fission and inheritance; self assembles on the cytoplasmic face of mitochondrial tubules at sites where division will occur; participates in endocytosis and regulates peroxisome fission along with Vps1p; mutants in the human ortholog DNM1L, which mediates mitochondrial fission, peroxisomal division, autophagy, and mitophagy, are associated with slowly progressive infantile encephalopathy [Source:SGD;Acc:S000003924]
Gene families : OG_03_0001455 (OF) Phylogenetic Tree(s): OG0001455_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YLL001W | |
Cluster | HCCA: Cluster_68 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AOA69286 | No alias | Dynamin central domain | 0.03 | OF | |
CAK38452 | No alias | Dynamin GTPase effector domain | 0.02 | OF | |
CBF84760 | No alias | dynamin-like GTPase Dnm1, putative | 0.03 | OF | |
ESU06621 | No alias | dynamin-1 | 0.02 | OF | |
KHC79091 | No alias | dynamin GTPase;Dynamin central region;Dynamin GTPase... | 0.06 | OF | |
SPBC12C2.08.1 | No alias | mitochondrial dynamin family GTPase Dnm1... | 0.03 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0003924 | GTPase activity | IEA | Interproscan |
MF | GO:0005525 | GTP binding | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
No external refs found! |