Description : Dynamin-related GTPase involved in mitochondrial organization; required for mitochondrial fission and inheritance; self assembles on the cytoplasmic face of mitochondrial tubules at sites where division will occur; participates in endocytosis and regulates peroxisome fission along with Vps1p; mutants in the human ortholog DNM1L, which mediates mitochondrial fission, peroxisomal division, autophagy, and mitophagy, are associated with slowly progressive infantile encephalopathy [Source:SGD;Acc:S000003924]

Gene families : OG_03_0001455 (OF) Phylogenetic Tree(s): OG0001455_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR: YLL001W
Cluster HCCA: Cluster_68

Target Alias Description ECC score Gene Family Method Actions
AOA69286 No alias Dynamin central domain 0.03 OF
CAK38452 No alias Dynamin GTPase effector domain 0.02 OF
CBF84760 No alias dynamin-like GTPase Dnm1, putative 0.03 OF
ESU06621 No alias dynamin-1 0.02 OF
KHC79091 No alias dynamin GTPase;Dynamin central region;Dynamin GTPase... 0.06 OF
SPBC12C2.08.1 No alias mitochondrial dynamin family GTPase Dnm1... 0.03 OF

Type GO Term Name Evidence Source
MF GO:0003924 GTPase activity IEA Interproscan
MF GO:0005525 GTP binding IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR022812 Dynamin_SF 31 245
IPR000375 Dynamin_central 255 540
IPR003130 GED 665 755
No external refs found!