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  5. YKR086W

YKR086W


Description : DEAH-box RNA helicase involved in second catalytic step of splicing and in exon ligation; exhibits ATP-dependent RNA unwinding activity; mediates the release of Yju2p and Cwc25p in the second step; in the absence of ATP, stabilizes the binding of Cwc25p to the spliceosome in the first catalytic step; missense mutation in human ortholog DHX38 associated with early-onset retinitis pigmentosa [Source:SGD;Acc:S000001794]


Gene families : OG_03_0000045 (OF) Phylogenetic Tree(s): OG0000045_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YKR086W
Cluster HCCA: Cluster_59

Target Alias Description ECC score Gene Family Method Actions
AFR93170 No alias ATP-dependent RNA helicase DDX35;AAA domain;Helicase... 0.03 OF
AFR95524 No alias pre-mRNA-splicing factor ATP-dependent RNA helicase... 0.03 OF
AFR97936 No alias pre-mRNA-splicing factor ATP-dependent RNA helicase... 0.08 OF
AOA65445 No alias Helicase-associated domain 0.03 OF
AOA66220 No alias Helicase, C-terminal 0.05 OF
CAG80826 No alias Domain of unknown function DUF1605 0.03 OF
CAG82909 No alias Helicase, C-terminal 0.04 OF
CAK46614 No alias Oligonucleotide/oligosaccharide-binding (OB)-fold 0.02 OF
CAK97428 No alias Helicase associated domain (HA2) 0.02 OF
CBF70766 No alias mRNA splicing factor RNA helicase 0.07 OF
CBF74845 No alias mRNA splicing factor RNA helicase 0.05 OF
CBF76926 No alias hypothetical protein similar to ATP dependent helicase 0.06 OF
EAA35453 No alias Domain of unknown function DUF1605 0.02 OF
EAA35877 No alias Helicase, C-terminal 0.02 OF
EAL88094 No alias mRNA splicing factor RNA helicase (Prp16), putative 0.02 OF
EAL91525 No alias RNA helicase-like splicing factor (HRH1), putative 0.04 OF
EAL93068 No alias mRNA splicing factor RNA helicase (Cdc28), putative 0.09 OF
EAU85197 No alias ATP-dependent RNA helicase Prp43 0.02 OF
EAU85955 No alias pre-mRNA splicing factor 0.03 OF
EAU86151 No alias ATP-dependent RNA helicase Prh1 0.01 OF
EAU92580 No alias ATP-dependent RNA helicase DHX8 0.05 OF
EAU93276 No alias pre-mRNA splicing factor 0.02 OF
EDN95366 No alias Helicase, C-terminal 0.03 OF
EDN99006 No alias Helicase-associated domain 0.05 OF
EDO00044 No alias DEAD/DEAH box helicase domain 0.03 OF
EED80851 No alias S1 domain 0.02 OF
EGR45053 No alias Helicase-associated domain 0.03 OF
EGR47965 No alias Helicase-associated domain 0.02 OF
EGR50716 No alias Helicase, C-terminal 0.07 OF
EJF55621 No alias Helicase conserved C-terminal domain 0.05 OF
EJF57706 No alias DEAD/DEAH box helicase 0.03 OF
ESU05632 No alias pre-mRNA-splicing factor ATP-dependent RNA helicase prp16 0.03 OF
ESU10905 No alias ATP-dependent RNA helicase DHX8 0.04 OF
ESU17099 No alias Helicase, C-terminal 0.04 OF
KHC71219 No alias pre-mRNA-splicing factor ATP-dependent RNA helicase... 0.08 OF
KHC75427 No alias ATP-dependent RNA helicase DHX8/PRP22;Helicase... 0.05 OF
KHC78967 No alias pre-mRNA-splicing factor ATP-dependent RNA helicase-like... 0.02 OF
MGG_02518T0 No alias ATP-dependent RNA helicase DHX8... 0.02 OF
MGG_07501T0 No alias ATP-dependent RNA helicase DHX8... 0.03 OF
MGG_08807T0 No alias Pre-mRNA-splicing factor ATP-dependent RNA helicase... 0.02 OF
POW03903 No alias Domain of unknown function DUF1605 0.02 OF
POW10235 No alias Domain of unknown function DUF1605;Helicase,... 0.04 OF
POW17111 No alias Domain of unknown function DUF1605;Helicase,... 0.03 OF
SPAC10F6.02c.1 No alias ATP-dependent RNA helicase Prp22... 0.07 OF
SPAC20H4.09.1 No alias ATP-dependent RNA helicase, spliceosomal (predicted)... 0.02 OF
SPAC2G11.11c.1 No alias ATP-dependent RNA helicase Prh1 (predicted)... 0.03 OF
SPBC19C2.01.1 No alias ATP-dependent RNA helicase Cdc28 [Source:PomBase;Acc:SPBC19C2.01] 0.05 OF

Type GO Term Name Evidence Source
MF GO:0003676 nucleic acid binding IEA Interproscan
MF GO:0004386 helicase activity IEA Interproscan
MF GO:0005524 ATP binding IEA Interproscan
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Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence
InterPro domains Description Start Stop
IPR001650 Helicase_C 562 693
IPR011545 DEAD/DEAH_box_helicase_dom 357 511
IPR007502 Helicase-assoc_dom 760 845
IPR011709 DUF1605 903 980
No external refs found!