Description : Alpha arrestin, substrate of calcineurin; controls nutrient-mediated intracellular sorting of permease Gap1p; interacts with AP-1 subunit Apl4p; dephosphorylation of Aly1p required for the endocytosis of Dip5p; may regulate endocytosis of plasma membrane proteins by recruiting ubiquitin ligase Rsp5p to plasma membrane targets; ALY1 has a paralog, ALY2, that arose from the whole genome duplication [Source:SGD;Acc:S000001729]
Gene families : OG_03_0000873 (OF) Phylogenetic Tree(s): OG0000873_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YKR021W | |
Cluster | HCCA: Cluster_32 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AFR95488 | No alias | cyclin binding protein;Arrestin (or S-antigen),... | 0.03 | OF | |
EED85331 | No alias | Arrestin C-terminal-like domain | 0.03 | OF | |
EGR50344 | No alias | Arrestin C-terminal-like domain | 0.02 | OF | |
EJF57554 | No alias | Arrestin (or S-antigen), C-terminal domain | 0.01 | OF | |
KHC73454 | No alias | hypothetical protein;"Arrestin (or S-antigen),... | 0.05 | OF | |
SPBC2D10.04.1 | No alias | arrestin Aly1 related, implicated in endocytosis... | 0.03 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No GO annotation available for this sequence |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR011022 | Arrestin_C-like | 347 | 517 |
No external refs found! |