Description : Endosomal Rab family GTPase; required for vacuolar protein sorting, endocytosis and multivesicular body (MVB) biogenesis and sorting; required for localization of the CORVET complex to endosomes; involved in autophagy and ionic stress tolerance; similar to Vps21p and Ypt53p; mammalian Rab5 homolog; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001722]
Gene families : OG_03_0000375 (OF) Phylogenetic Tree(s): OG0000375_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YKR014C | |
Cluster | HCCA: Cluster_64 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AOA70409 | No alias | Small GTPase | 0.03 | OF | |
CAG80705 | No alias | Small GTPase | 0.02 | OF | |
CAL00639 | No alias | Ras family | 0.02 | OF | |
EAA26716 | No alias | Small GTPase | 0.05 | OF | |
EAA35575 | No alias | Small GTPase | 0.03 | OF | |
EAL89984 | No alias | RAB GTPase Ypt5, putative | 0.03 | OF | |
EGR46648 | No alias | Small GTPase | 0.04 | OF | |
ESU11469 | No alias | vacuolar protein sorting-associated protein 21 | 0.02 | OF | |
KHC70660 | No alias | vacuolar protein sorting-associated protein 21;Ras family | 0.04 | OF | |
KHC70668 | No alias | vacuolar protein sorting-associated protein 21;Ras family | 0.04 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0003924 | GTPase activity | IEA | Interproscan |
MF | GO:0005525 | GTP binding | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR001806 | Small_GTPase | 5 | 194 |
No external refs found! |