YKL217W


Description : Monocarboxylate/proton symporter of the plasma membrane; transport activity is dependent on the pH gradient across the membrane; mediates high-affinity uptake of carbon sources lactate, pyuvate, and acetate, and also of the micronutrient selenite, whose structure mimics that of monocarboxylates; expression and localization are tightly regulated, with transcription repression, mRNA degradation, and protein endocytosis and degradation all occurring in the presence of glucose [Source:SGD;Acc:S000001700]


Gene families : OG_03_0000488 (OF) Phylogenetic Tree(s): OG0000488_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YKL217W
Cluster HCCA: Cluster_26

Target Alias Description ECC score Gene Family Method Actions
AFR97514 No alias MFS transporter, SHS family, lactate transporter;Sugar... 0.04 OF
CAG82410 No alias Major facilitator, sugar transporter-like 0.03 OF
CBF70194 No alias carboxylic acid transport protein 0.03 OF
EAA32361 No alias Major facilitator, sugar transporter-like 0.04 OF
EAL86916 No alias sugar transporter family protein 0.05 OF
EAL93241 No alias carboxylic acid transport protein 0.04 OF
ESU11911 No alias Major facilitator, sugar transporter-like 0.04 OF
KHC76508 No alias sialate H+ symporter (SHS) family MFS transporter;Sugar... 0.05 OF
KHC79199 No alias sialate H+ symporter (SHS) family MFS transporter;Sugar... 0.03 OF

Type GO Term Name Evidence Source
CC GO:0016021 integral component of membrane IEA Interproscan
MF GO:0022857 transmembrane transporter activity IEA Interproscan
BP GO:0055085 transmembrane transport IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR005828 MFS_sugar_transport-like 127 562
No external refs found!