YKL213C


Description : WD repeat protein required for ubiquitin-mediated protein degradation; ubiquitin binding cofactor that complexes with Cdc48p; required for ribophagy; controls cellular ubiquitin concentration; promotes efficient NHEJ in postdiauxic/stationary phase; facilitates N-terminus-dependent proteolysis of centromeric histone H3 (Cse4p) for faithful chromosome segregation; protein increases in abundance and relocalizes from nucleus to nuclear periphery upon DNA replication stress [Source:SGD;Acc:S000001696]


Gene families : OG_03_0001769 (OF) Phylogenetic Tree(s): OG0001769_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YKL213C
Cluster HCCA: Cluster_24

Target Alias Description ECC score Gene Family Method Actions
POV98243 No alias WD40 repeat;WD40 repeat;WD40 repeat;WD40 repeat;WD40... 0.01 OF

Type GO Term Name Evidence Source
MF GO:0005515 protein binding IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR015155 PFU 333 441
IPR001680 WD40_repeat 211 247
IPR001680 WD40_repeat 90 125
IPR001680 WD40_repeat 128 165
IPR001680 WD40_repeat 4 40
IPR013535 PUL_dom 467 712
No external refs found!