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  5. YKL209C

YKL209C


Description : Plasma membrane ATP-binding cassette (ABC) transporter; required for the export of a-factor, catalyzes ATP hydrolysis coupled to a-factor transport; contains 12 transmembrane domains and two ATP binding domains; expressed only in MATa cells; human homolog ABCB1 mediates multidrug resistance in many chemotherapy-resistant tumors by effluxing toxic compounds from the cell [Source:SGD;Acc:S000001692]


Gene families : OG_03_0000037 (OF) Phylogenetic Tree(s): OG0000037_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YKL209C
Cluster HCCA: Cluster_25

Target Alias Description ECC score Gene Family Method Actions
AFR93103 No alias ATP-binding cassette, subfamily B (MDR/TAP), member... 0.04 OF
AOA68856 No alias ABC transporter-like 0.04 OF
CAG78460 No alias ABC transporter-like 0.02 OF
CAK45508 No alias ABC transporter transmembrane region 0.01 OF
CBF69884 No alias ABC multidrug transporter 0.02 OF
CBF89553 No alias AtrH 0.04 OF
EAA29359 No alias ABC transporter-like 0.02 OF
EAL89381 No alias ABC multidrug transporter, putative 0.02 OF
EAU86002 No alias multidrug resistance protein 1 0.02 OF
EED54722 No alias multidrug resistance protein 1, 2, putative 0.03 OF
EGR45959 No alias ABC transporter type 1, transmembrane domain 0.01 OF
EGR52477 No alias ABC transporter-like 0.01 OF
ESU13785 No alias ABC transporter-like 0.02 OF
KHC79192 No alias alpha-factor-transporting ATPase;ABC transporter... 0.14 OF
MGG_13762T0 No alias Multidrug resistance protein 3... 0.01 OF
SPBC25B2.02c.1 No alias M-factor transmembrane transporter Mam1... 0.03 OF

Type GO Term Name Evidence Source
MF GO:0005524 ATP binding IEA Interproscan
CC GO:0016021 integral component of membrane IEA Interproscan
MF GO:0016887 ATPase activity IEA Interproscan
MF GO:0042626 ATPase-coupled transmembrane transporter activity IEA Interproscan
BP GO:0055085 transmembrane transport IEA Interproscan
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Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence
InterPro domains Description Start Stop
IPR011527 ABC1_TM_dom 717 992
IPR011527 ABC1_TM_dom 27 304
IPR003439 ABC_transporter-like 1070 1218
IPR003439 ABC_transporter-like 375 533
No external refs found!