YKL145W

Description : ATPase of the 19S regulatory particle of the 26S proteasome; one of six ATPases of the regulatory particle; involved in the degradation of ubiquitinated substrates; required for optimal CDC20 transcription; interacts with Rpn12p and Ubr1p; mutant has aneuploidy tolerance [Source:SGD;Acc:S000001628]

Gene families : OG_03_0002305 (OF) Phylogenetic Tree(s): OG0002305_tree

Sequence : coding (download), protein (download)

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Type	Description	Actions
Neighborhood	HRR: YKL145W
Cluster	HCCA: Cluster_33

Target	Alias	Description	ECC score	Gene Family Method
AFR96443	No alias	26S protease regulatory subunit 7;ATPase family...	0.22	OF
AOA70345	No alias	ATPase, AAA-type, core	0.26	OF
CAG80886	No alias	AAA ATPase, AAA+ lid domain	0.12	OF
CAK44546	No alias	ATPase family associated with various cellular activities (AAA)	0.22	OF
CBF83751	No alias	hypothetical protein similar to 26S proteasome regulatory subunit	0.18	OF
EAA34894	No alias	ATPase, AAA-type, core	0.34	OF
EAL92793	No alias	proteasome regulatory particle subunit Rpt1, putative	0.11	OF
EDN96899	No alias	ATPase, AAA-type, core	0.12	OF
EED84180	No alias	ATPase, AAA-type, core	0.02	OF
EFI28421	No alias	prsS7	0.11	OF
EGR52669	No alias	ATPase, AAA-type, core	0.29	OF
ESU05755	No alias	26S protease regulatory subunit 7	0.18	OF
KHC83300	No alias	26S proteasome subunit P45 family protein;AAA+ lid...	0.22	OF
MGG_01581T0	No alias	26S protease regulatory subunit 7...	0.05	OF
POW02739	No alias	AAA ATPase, AAA+ lid domain;ATPase, AAA-type, core	0.03	OF
SPBC16C6.07c.1	No alias	19S proteasome regulatory subunit Rpt1 (predicted)...	0.09	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
MF	GO:0008144	drug binding	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR003959	ATPase_AAA_core	246	378
IPR041569	AAA_lid_3	407	444

External Links

No external refs found!

YKL145W

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation