Description : Hsp70 (Ssa1p) nucleotide exchange factor; required for the release of misfolded proteins from the Hsp70 system to the Ub-proteasome machinery for destruction; cytosolic homolog of Sil1p, which is the nucleotide exchange factor for BiP (Kar2p) in the endoplasmic reticulum; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000000305]
Gene families : OG_03_0002265 (OF) Phylogenetic Tree(s): OG0002265_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YBR101C | |
Cluster | HCCA: Cluster_30 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AFR94958 | No alias | hsp70-like protein;Nucleotide exchange factor Fes1 | 0.16 | OF | |
AOA67184 | No alias | Nucleotide exchange factor Fes1 | 0.2 | OF | |
CAG78080 | No alias | Nucleotide exchange factor Fes1 | 0.2 | OF | |
CAK42224 | No alias | HEAT repeats | 0.09 | OF | |
CBF70954 | No alias | Hsp70 nucleotide exchange factor fes1 | 0.21 | OF | |
EAA31494 | No alias | Nucleotide exchange factor Fes1 | 0.1 | OF | |
EAL85565 | No alias | Hsp70 nucleotide exchange factor (Fes1), putative | 0.13 | OF | |
EGR53087 | No alias | Nucleotide exchange factor Fes1 | 0.1 | OF | |
ESU13578 | No alias | Nucleotide exchange factor Fes1 | 0.12 | OF | |
KHC73228 | No alias | hsp70-like protein;Nucleotide exchange factor Fes1 | 0.15 | OF | |
MGG_03983T0 | No alias | Hsp70-like protein [Source:UniProtKB/TrEMBL;Acc:G4NGZ3] | 0.08 | OF | |
POW05605 | No alias | Nucleotide exchange factor Fes1 | 0.02 | OF | |
SPBC3B9.01.1 | No alias | Hsp70 nucleotide exchange factor Fes1 (predicted)... | 0.2 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No GO annotation available for this sequence |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR013918 | Nucleotide_exch_fac_Fes1 | 1 | 82 |
No external refs found! |