Description : 5' to 3' exonuclease, 5' flap endonuclease; required for Okazaki fragment processing and maturation, for long-patch base-excision repair and large loop repair (LLR), ribonucleotide excision repair; member of the S. pombe RAD2/FEN1 family; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000001596]
Gene families : OG_03_0000966 (OF) Phylogenetic Tree(s): OG0000966_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
| Type | Description | Actions |
|---|---|---|
| Neighborhood | HRR: YKL113C | |
| Cluster | HCCA: Cluster_13 |
| Target | Alias | Description | ECC score | Gene Family Method | Actions |
|---|---|---|---|---|---|
| AFR95156 | No alias | flap endonuclease 1;XPG N-terminal domain;XPG I-region | 0.03 | OF | |
| AOA66839 | No alias | XPG-I domain | 0.03 | OF | |
| CAG78455 | No alias | XPG N-terminal | 0.07 | OF | |
| EDN95298 | No alias | XPG N-terminal | 0.04 | OF | |
| EDO65264 | No alias | XPG N-terminal | 0.05 | OF | |
| KHC71401 | No alias | flap endonuclease 1;XPG N-terminal domain;XPG I-region | 0.04 | OF | |
| MGG_03419T0 | No alias | Flap endonuclease 1 [Source:UniProtKB/Swiss-Prot;Acc:A4QS18] | 0.02 | OF |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
| MF | GO:0004518 | nuclease activity | IEA | Interproscan |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
No Predicted GO terms available for this sequence |
| No external refs found! |