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  5. YKL108W

YKL108W


Description : Single-stranded DNA origin-binding and annealing protein; required for initiation of DNA replication; phosphorylated in S phase by cyclin-dependent kinases (Cdks), promoting origin binding, DNA replication and Dpb11p complex formation; component of the preloading complex; binds the Mcm2-7p complex to prevent inappropriate Mcm2-7p interaction with the GINS complex in G1; required for S phase checkpoint; relative distribution to the nucleus increases upon DNA replication stress [Source:SGD;Acc:S000001591]


Gene families : OG_03_0003803 (OF) Phylogenetic Tree(s): OG0003803_tree

Sequence : coding (download), protein (download)


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Type Description Actions
Neighborhood HRR: YKL108W
Cluster HCCA: Cluster_15

Target Alias Description ECC score Gene Family Method Actions
ESU18017 No alias DNA replication/checkpoint protein 0.02 OF

Type GO Term Name Evidence Source

No GO annotation available for this sequence
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Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence
InterPro domains Description Start Stop
IPR021110 DNA_rep_checkpnt_protein 7 73
IPR021110 DNA_rep_checkpnt_protein 79 453
No external refs found!