YKL032C


Description : Transcriptional repressor that regulates hypoxic genes during normoxia; involved in the aerobic repression of genes such as COX5b, TIR1, and HEM13; binds DNA intrastrand cross-links formed by cisplatin; HMG (high mobility group box) domain containing protein which binds and bends cisplatin-modified DNA, blocking excision repair; IXR1 has a paralog, ABF2, that arose from the whole genome duplication [Source:SGD;Acc:S000001515]


Gene families : OG_03_0000436 (OF) Phylogenetic Tree(s): OG0000436_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YKL032C
Cluster HCCA: Cluster_61

Target Alias Description ECC score Gene Family Method Actions
EJF61605 No alias HMG (high mobility group) box 0.02 OF
POW11872 No alias High mobility group box domain 0.02 OF
SPBC28F2.11.1 No alias HMG box protein Hmo1 [Source:PomBase;Acc:SPBC28F2.11] 0.03 OF

Type GO Term Name Evidence Source

No GO annotation available for this sequence

Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR009071 HMG_box_dom 361 428
IPR009071 HMG_box_dom 434 499
No external refs found!