Description : Transcriptional repressor that regulates hypoxic genes during normoxia; involved in the aerobic repression of genes such as COX5b, TIR1, and HEM13; binds DNA intrastrand cross-links formed by cisplatin; HMG (high mobility group box) domain containing protein which binds and bends cisplatin-modified DNA, blocking excision repair; IXR1 has a paralog, ABF2, that arose from the whole genome duplication [Source:SGD;Acc:S000001515]
Gene families : OG_03_0000436 (OF) Phylogenetic Tree(s): OG0000436_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YKL032C | |
Cluster | HCCA: Cluster_61 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
EJF61605 | No alias | HMG (high mobility group) box | 0.02 | OF | |
POW11872 | No alias | High mobility group box domain | 0.02 | OF | |
SPBC28F2.11.1 | No alias | HMG box protein Hmo1 [Source:PomBase;Acc:SPBC28F2.11] | 0.03 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No GO annotation available for this sequence |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
No external refs found! |