YJR131W


Description : Alpha-1,2-mannosidase; involved in ER-associated protein degradation (ERAD); catalyzes the removal of one mannose residue from a glycosylated protein, converting the modification from Man9GlcNAc to Man8GlcNAc; catalyzes the last step in glycoprotein maturation in the ER and is critical for ER protein degradation [Source:SGD;Acc:S000003892]


Gene families : OG_03_0001308 (OF) Phylogenetic Tree(s): OG0001308_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YJR131W
Cluster HCCA: Cluster_39

Target Alias Description ECC score Gene Family Method Actions
AOA68147 No alias Glycoside hydrolase family 47 0.02 OF
CAK43347 No alias Glycosyl hydrolase family 47 0.01 OF
EAA35037 No alias Glycoside hydrolase family 47 0.01 OF
EDO02037 No alias Glycoside hydrolase family 47 0.01 OF
KHC83150 No alias mannosyl-oligosaccharide 1,2-alpha-mannosidase;Glycosyl... 0.02 OF

Type GO Term Name Evidence Source
MF GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity IEA Interproscan
MF GO:0005509 calcium ion binding IEA Interproscan
CC GO:0016020 membrane IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR001382 Glyco_hydro_47 45 532
No external refs found!