Description : Ubiquitin-conjugating enzyme (E2); key E2 partner with Ubc1p for the anaphase-promoting complex (APC); mediates degradation of abnormal or excess proteins, including calmodulin and histone H3; regulates levels of DNA Polymerase-{alpha} to promote efficient and accurate DNA replication; interacts with many SCF ubiquitin protein ligases; component of the cellular stress response; UBC4 has a paralog, UBC5, that arose from the whole genome duplication [Source:SGD;Acc:S000000286]
Gene families : OG_03_0000225 (OF) Phylogenetic Tree(s): OG0000225_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
| Type | Description | Actions |
|---|---|---|
| Neighborhood | HRR: YBR082C | |
| Cluster | HCCA: Cluster_30 |
| Target | Alias | Description | ECC score | Gene Family Method | Actions |
|---|---|---|---|---|---|
| AFR94994 | No alias | ubiquitin-conjugating enzyme E2 D/E;Ubiquitin-conjugating enzyme | 0.01 | OF | |
| AOA68486 | No alias | Ubiquitin-conjugating enzyme E2 | 0.03 | OF | |
| CBF79830 | No alias | ubiquitin conjugating enzyme | 0.02 | OF | |
| MGG_00103T0 | No alias | Ubiquitin-conjugating enzyme [Source:UniProtKB/TrEMBL;Acc:G4NEH5] | 0.01 | OF | |
| MGG_00180T0 | No alias | Ubiquitin-conjugating enzyme [Source:UniProtKB/TrEMBL;Acc:G4NDX5] | 0.01 | OF |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
No GO annotation available for this sequence |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
No Predicted GO terms available for this sequence |
| InterPro domains | Description | Start | Stop |
|---|---|---|---|
| IPR000608 | UBQ-conjugat_E2 | 6 | 142 |
| No external refs found! |