Description : Member of the conserved GPN-loop GTPase family; has a role in transport of RNA polymerase II to the nucleus; exhibits GTP-dependent binding to PolII; has ATPase activity; involved in sister chromatid cohesion; phosphorylated by the Pcl1p-Pho85p kinase complex; human homolog XAB1 interacts with human RNA polymerase II; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003833]
Gene families : OG_03_0003222 (OF) Phylogenetic Tree(s): OG0003222_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YJR072C | |
Cluster | HCCA: Cluster_13 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AOA68948 | No alias | GPN-loop GTPase | 0.03 | OF | |
CAG79832 | No alias | GPN-loop GTPase | 0.02 | OF | |
KHC71928 | No alias | GTPase NPA3;Conserved hypothetical ATP binding protein | 0.03 | OF | |
SPBC119.15.1 | No alias | RNA polymerase II binding AAA family ATPase Npa3... | 0.05 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No GO annotation available for this sequence |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR004130 | Gpn | 8 | 257 |
No external refs found! |