YJR017C


Description : Peptidylprolyl-cis/trans-isomerase (PPIase); specific for phosphorylated S/T residues N-terminal to proline; regulates phosphorylation of RNAPII large subunit (Rpo21p) C-terminal domain (CTD) at Ser7; associates with phospho-Ser5 form of RNAPII in vivo; present along entire coding length of genes; represses initiation of CUTs; required for efficient termination of mRNA transcription, trimethylation of histone H3; human ortholog PIN1 can complement yeast null and ts mutants [Source:SGD;Acc:S000003778]


Gene families : OG_03_0002423 (OF) Phylogenetic Tree(s): OG0002423_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YJR017C
Cluster HCCA: Cluster_35


Type GO Term Name Evidence Source
MF GO:0003755 peptidyl-prolyl cis-trans isomerase activity IEA Interproscan
MF GO:0005515 protein binding IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR000297 PPIase_PpiC 64 168
IPR001202 WW_dom 11 41
No external refs found!