Description : Lsm (Like Sm) protein; forms heteroheptameric complex (with Lsm2p, Lsm3p, Lsm4p, Lsm5p, Lsm6p, and Lsm7p) involved in degradation of cytoplasmic mRNAs; also enters the nucleus and positively regulates transcription initiation; unlike most Sm-like proteins, Lsm1p requires both its SM-domain and C-terminal domain for RNA-binding; binds to mRNAs under glucose starvation, most often in the 3' UTR; forms cytoplasmic foci upon DNA replication stress [Source:SGD;Acc:S000003660]
Gene families : OG_03_0002104 (OF) Phylogenetic Tree(s): OG0002104_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YJL124C | |
Cluster | HCCA: Cluster_51 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AFR94245 | No alias | U6 snRNA-associated Sm-like protein LSm1;LSM domain | 0.02 | OF | |
EAA27276 | No alias | LSM domain, eukaryotic/archaea-type | 0.02 | OF | |
EAU93018 | No alias | LSM domain, eukaryotic/archaea-type | 0.02 | OF | |
ESU17890 | No alias | LSM domain, eukaryotic/archaea-type | 0.03 | OF | |
KHC69643 | No alias | U6 snRNA-associated Sm-like protein LSm1;LSM domain | 0.04 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No GO annotation available for this sequence |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR001163 | LSM_dom_euk/arc | 48 | 113 |
No external refs found! |