Description : Nucleosome assembly factor; involved in chromatin assembly, disassembly; required for recovery after DSB repair; role in H3K56 acetylation required for expression homeostasis, buffering mRNA synthesis rate against gene dosage changes in S phase; anti-silencing protein, derepresses silent loci when overexpressed; role in regulating Ty1 transposition; relocalizes to cytosol under hypoxia; growth defect of asf1 null is functionally complemented by either human ASF1A or ASF1B [Source:SGD;Acc:S000003651]
Gene families : OG_03_0002567 (OF) Phylogenetic Tree(s): OG0002567_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YJL115W | |
Cluster | HCCA: Cluster_5 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
ESU05522 | No alias | Histone chaperone ASF1-like | 0.02 | OF | |
KHC70642 | No alias | histone chaperone ASF1;ASF1 like histone chaperone | 0.06 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
CC | GO:0005634 | nucleus | IEA | Interproscan |
BP | GO:0006333 | chromatin assembly or disassembly | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR006818 | ASF1-like | 1 | 154 |
No external refs found! |