Description : Component of the spindle-assembly checkpoint complex; delays onset of anaphase in cells with defects in mitotic spindle assembly; forms a complex with Mad1p; regulates APC/C activity during prometaphase and metaphase of meiosis I; gene dosage imbalance between MAD1 and MAD2 leads to chromosome instability [Source:SGD;Acc:S000003567]
Gene families : OG_03_0003521 (OF) Phylogenetic Tree(s): OG0003521_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YJL030W | |
Cluster | HCCA: Cluster_46 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
CAG79505 | No alias | HORMA domain | 0.03 | OF | |
CBF87000 | No alias | mitotic spindle checkpoint protein | 0.06 | OF | |
EAL92154 | No alias | mitotic spindle checkpoint protein (Mad2), putative | 0.05 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No GO annotation available for this sequence |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR003511 | HORMA_dom | 10 | 174 |
No external refs found! |