Description : Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p; associates with actin patches on cell cortex; promotes protein-protein interactions essential for endocytosis; binds to and activates Arp2/3 complex in vitro; phosphorylation of Thr-1225 is regulated by MAPK Hog1p in response to osmotic stress; previously thought to be a subunit of poly(A) ribonuclease [Source:SGD;Acc:S000001445]
Gene families : OG_03_0002107 (OF) Phylogenetic Tree(s): OG0002107_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YIR006C | |
Cluster | HCCA: Cluster_56 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AFR96434 | No alias | multidomain RhoGEF;Pleckstrin homology domain;WH2... | 0.04 | OF | |
AOA68617 | No alias | Domain of unknown function DUF1720 | 0.1 | OF | |
CAG81042 | No alias | EH domain | 0.07 | OF | |
CAK46430 | No alias | Domain of unknown function (DUF1720) | 0.05 | OF | |
CBF74351 | No alias | Actin cytoskeleton-regulatory complex protein pan1 | 0.09 | OF | |
EAA33504 | No alias | EH domain | 0.06 | OF | |
EAL87083 | No alias | actin cortical patch assembly protein Pan1, putative | 0.12 | OF | |
EAU81913 | No alias | Dbl homology (DH) domainSH3 domainSH3 domainEH... | 0.06 | OF | |
EDO03506 | No alias | EH domain | 0.04 | OF | |
EGR52784 | No alias | WH2 domain | 0.09 | OF | |
EJF56295 | No alias | Variant SH3 domain | 0.03 | OF | |
ESU13109 | No alias | EH domain | 0.08 | OF | |
KHC81398 | No alias | actin cytoskeleton-regulatory complex protein... | 0.11 | OF | |
SPAC25G10.09c.1 | No alias | actin cortical patch component, with EF hand and WH2... | 0.07 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0005515 | protein binding | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
No external refs found! |