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  5. YIL143C

YIL143C


Description : Component of RNA polymerase transcription factor TFIIH holoenzyme; acts as dsDNA-dependent translocase in context of TFIIH, unwinds DNA strands during initiation and promotes transcription start site (TSS) scanning; has DNA-dependent ATPase/helicase activity; interacts functionally with TFIIB, has roles in TSS selection and gene looping to juxtapose initiation and termination regions; involved in DNA repair; relocalizes to cytosol under hypoxia; homolog of human ERCC3 [Source:SGD;Acc:S000001405]


Gene families : OG_03_0003531 (OF) Phylogenetic Tree(s): OG0003531_tree

Sequence : coding (download), protein (download)


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Type Description Actions
Neighborhood HRR: YIL143C
Cluster HCCA: Cluster_33

Target Alias Description ECC score Gene Family Method Actions
CAG83021 No alias Helicase/UvrB, N-terminal 0.05 OF
EAL85973 No alias TFIIH complex helicase Ssl2, putative 0.02 OF
ESU13514 No alias DNA repair helicase RAD25 0.02 OF
KHC71256 No alias DNA repair helicase RAD25;ERCC3/RAD25/XPB C-terminal... 0.03 OF

Type GO Term Name Evidence Source
MF GO:0003677 DNA binding IEA Interproscan
MF GO:0005524 ATP binding IEA Interproscan
MF GO:0016787 hydrolase activity IEA Interproscan
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Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence
InterPro domains Description Start Stop
IPR032830 XPB/Ssl2_N 133 256
IPR006935 Helicase/UvrB_N 361 517
IPR032438 ERCC3_RAD25_C 543 777
No external refs found!