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YIL030C


Description : Membrane-embedded ubiquitin-protein ligase; ER and inner nuclear membrane localized RING-CH domain E3 ligase involved in ER-associated protein degradation (ERAD); targets misfolded cytosolic/nucleoplasmic domains of soluble and membrane embedded proteins (ERAD-C) and a transmembrane domain containing substrate (ERAD-M), Sbh2p; C-terminal element (CTE), conserved in human ortholog MARCH10/TEB4, determines substrate selectivity [Source:SGD;Acc:S000001292]


Gene families : OG_03_0002403 (OF) Phylogenetic Tree(s): OG0002403_tree

Sequence : coding (download), protein (download)


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Type Description Actions
Neighborhood HRR: YIL030C
Cluster HCCA: Cluster_39

Target Alias Description ECC score Gene Family Method Actions
AFR95924 No alias E3 ubiquitin-protein ligase MARCH6;RING-variant domain 0.06 OF
CBF70108 No alias RING finger membrane protein 0.06 OF
EAL93161 No alias RING finger membrane protein 0.05 OF
EGR45697 No alias Zinc finger, RING-CH-type 0.02 OF
KHC71959 No alias E3 ubiquitin-protein ligase MARCH6;RING-variant domain 0.07 OF
POW04071 No alias Zinc finger, RING-CH-type 0.02 OF

Type GO Term Name Evidence Source
MF GO:0008270 zinc ion binding IEA Interproscan
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Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence
InterPro domains Description Start Stop
IPR011016 Znf_RING-CH 39 93
No external refs found!