YBR008C


Description : Plasma membrane transporter of the major facilitator superfamily; member of the 12-spanner drug:H(+) antiporter DHA1 family; involved in efflux of fluconazole, diazaborine, benomyl, methotrexate, and other drugs; expression induced in cells treated with the mycotoxin patulin; relocalizes from nucleus to plasma membrane upon DNA replication stress [Source:SGD;Acc:S000000212]


Gene families : OG_03_0000001 (OF) Phylogenetic Tree(s): OG0000001_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YBR008C
Cluster HCCA: Cluster_19

Target Alias Description ECC score Gene Family Method Actions
AFR95896 No alias MFS transporter;Major Facilitator Superfamily 0.02 OF
AFR96710 No alias polyamine transporter 1;Major Facilitator Superfamily 0.03 OF
AOA65538 No alias Major facilitator superfamily 0.03 OF
AOA65607 No alias Major facilitator superfamily 0.12 OF
CAG77953 No alias Major facilitator superfamily 0.02 OF
CAG78193 No alias Major facilitator superfamily 0.04 OF
CAG81743 No alias Major facilitator superfamily 0.02 OF
CAG84030 No alias Major facilitator superfamily 0.03 OF
CAK37865 No alias Major Facilitator Superfamily 0.02 OF
CAK37933 No alias Major Facilitator Superfamily 0.02 OF
CAK40158 No alias Major Facilitator Superfamily 0.02 OF
CAK41473 No alias Major Facilitator Superfamily 0.03 OF
CAK43124 No alias Major Facilitator Superfamily 0.02 OF
CAK43419 No alias Major Facilitator Superfamily 0.03 OF
CAK44749 No alias Major Facilitator Superfamily 0.02 OF
CAK44796 No alias Major Facilitator Superfamily 0.02 OF
CAK45769 No alias Major Facilitator Superfamily 0.02 OF
CAK46366 No alias Major Facilitator Superfamily 0.03 OF
CAK46688 No alias Major Facilitator Superfamily 0.02 OF
CAK48045 No alias Major Facilitator Superfamily 0.03 OF
CAK96519 No alias Major Facilitator Superfamily 0.02 OF
CAK96637 No alias Major Facilitator Superfamily 0.06 OF
CAK97044 No alias Major Facilitator Superfamily 0.02 OF
CAK97142 No alias Major Facilitator Superfamily 0.02 OF
CAK97325 No alias Major Facilitator Superfamily 0.03 OF
CBF74667 No alias conserved hypothetical protein 0.02 OF
CBF80125 No alias conserved hypothetical protein 0.02 OF
CBF83060 No alias MFS multidrug transporter, putative 0.03 OF
CBF87985 No alias MFS multidrug transporter, putative 0.02 OF
CBF90081 No alias conserved hypothetical protein 0.02 OF
EAA28541 No alias Major facilitator superfamily 0.03 OF
EAA30189 No alias Major facilitator superfamily 0.02 OF
EAA31306 No alias Major facilitator superfamily 0.03 OF
EAA34085 No alias Major facilitator superfamily 0.02 OF
EAA34915 No alias Major facilitator superfamily 0.03 OF
EAL84305 No alias MFS multidrug transporter, putative 0.03 OF
EAU89312 No alias multidrug resistance protein 4 0.02 OF
EDN94406 No alias Major facilitator superfamily 0.02 OF
EDN99438 No alias Major facilitator superfamily 0.02 OF
EDO03312 No alias Major facilitator superfamily 0.02 OF
EDO04881 No alias Major facilitator superfamily 0.02 OF
EED48277 No alias bicyclomycin resistance protein, putative 0.02 OF
EED54606 No alias conserved hypothetical protein 0.03 OF
EGR44089 No alias Major facilitator superfamily 0.03 OF
EGR44123 No alias Major facilitator superfamily 0.02 OF
EGR45679 No alias Major facilitator superfamily 0.04 OF
EGR46301 No alias Major facilitator superfamily 0.02 OF
EGR52691 No alias Major facilitator superfamily 0.05 OF
EGR52809 No alias Major facilitator superfamily 0.04 OF
EJF55857 No alias Major Facilitator Superfamily 0.11 OF
EJF59236 No alias Major Facilitator Superfamily 0.04 OF
EJF60613 No alias Major Facilitator Superfamily 0.09 OF
EJF61601 No alias Major Facilitator Superfamily 0.07 OF
ESU08799 No alias Major facilitator superfamily 0.02 OF
ESU09339 No alias Major facilitator superfamily 0.03 OF
ESU10051 No alias Major facilitator superfamily 0.04 OF
ESU10174 No alias Major facilitator superfamily 0.03 OF
KHC71338 No alias hypothetical protein;Major Facilitator Superfamily 0.08 OF
KHC73328 No alias hypothetical protein;Major Facilitator Superfamily 0.09 OF
KHC73453 No alias benomyl/methotrexate resistance protein;Major... 0.1 OF
MGG_00416T0 No alias MFS transporter [Source:UniProtKB/TrEMBL;Acc:G4NCC4] 0.02 OF
MGG_01511T0 No alias Benomyl/methotrexate resistance protein... 0.04 OF
MGG_03205T0 No alias Polyamine transporter 2 [Source:UniProtKB/TrEMBL;Acc:G4NAB4] 0.02 OF
MGG_05723T0 No alias Fluconazole resistance protein 1... 0.02 OF
MGG_10363T0 No alias Putative uncharacterized protein... 0.02 OF
SPAC11D3.05.1 No alias MFS family transmembrane transporter Mfs2 (predicted)... 0.03 OF
SPBC36.03c.1 No alias MFS family transmembrane transporter Mfs3... 0.03 OF
SPBC609.04.1 No alias spermine family transmembrane transporter Caf5... 0.05 OF
YOR273C No alias Polyamine transporter of the major facilitator... 0.02 OF

Type GO Term Name Evidence Source
MF GO:0022857 transmembrane transporter activity IEA Interproscan
BP GO:0055085 transmembrane transport IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR011701 MFS 109 490
No external refs found!