Description : Subunit of the Iml1p/SEACIT complex; SEACIT (Iml1p-Npr2p-Npr3p) is a subcomplex of SEAC, a coatomer-related complex that associates dynamically with the vacuole; Npr3p may have a structural or regulatory role, supporting Iml1p function as a GAP for the Rag family GTPase Gtr1p, and leading to inhibition of TORC1 signaling in response to amino acid deprivation; SEACIT is required for non-nitrogen-starvation-induced autophagy; null mutant has meiotic defects; human NPRL3 homolog [Source:SGD;Acc:S000001015]
Gene families : OG_03_0003895 (OF) Phylogenetic Tree(s): OG0003895_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YHL023C | |
Cluster | HCCA: Cluster_32 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AFR96239 | No alias | hypothetical protein;Nitrogen Permease regulator of... | 0.02 | OF | |
AOA66865 | No alias | Nitrogen permease regulator 3 | 0.03 | OF | |
CBF87783 | No alias | Protein rmd11 Precursor | 0.02 | OF | |
ESU06607 | No alias | Nitrogen permease regulator 3 | 0.06 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
BP | GO:0032007 | negative regulation of TOR signaling | IEA | Interproscan |
BP | GO:0034198 | cellular response to amino acid starvation | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR005365 | Npr3 | 399 | 966 |
No external refs found! |