Description : Flavin-dependent monooxygenase involved in ubiquinone biosynthesis; responsible for hydroxylation at position C5 and deamination at C4 during ubiquinone (Coenzyme Q) biosynthesis; localizes to matrix face of mitochondrial inner membrane in a large complex with other ubiquinone biosynthetic enzymes; human homolog COQ6 can complement yeast null mutant and is implicated in steroid-resistant nephrotic syndrome (SRNS) [Source:SGD;Acc:S000003487]
Gene families : OG_03_0003991 (OF) Phylogenetic Tree(s): OG0003991_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YGR255C | |
Cluster | HCCA: Cluster_46 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AFR96994 | No alias | ubiquinone biosynthesis monooxygenase COQ6;FAD binding domain | 0.02 | OF | |
AOA67974 | No alias | FAD-binding domain | 0.03 | OF | |
ESU05552 | No alias | FAD-binding domain | 0.03 | OF | |
MGG_11732T0 | No alias | Putative uncharacterized protein... | 0.02 | OF | |
SPBC146.12.1 | No alias | monooxygenase Coq6 (predicted) [Source:PomBase;Acc:SPBC146.12] | 0.03 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0071949 | FAD binding | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR002938 | FAD-bd | 28 | 404 |
No external refs found! |