YGR252W

Description : Catalytic subunit of ADA and SAGA histone acetyltransferase complexes; modifies N-terminal lysines on histones H2B and H3; acetylates Rsc4p, a subunit of the RSC chromatin-remodeling complex, altering replication stress tolerance; relocalizes to the cytosol in response to hypoxia; mutant displays reduced transcription elongation in the G-less-based run-on (GLRO) assay; greater involvement in repression of RNAPII-dependent transcription than in activation [Source:SGD;Acc:S000003484]

Gene families : OG_03_0000432 (OF) Phylogenetic Tree(s): OG0000432_tree

Sequence : coding (download), protein (download)

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Type	Description	Actions
Neighborhood	HRR: YGR252W
Cluster	HCCA: Cluster_5

Target	Alias	Description	ECC score	Gene Family Method	Actions
SPAC1952.05.1	No alias	SAGA complex histone acetyltransferase catalytic subunit...	0.02	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	IEA	Interproscan
MF	GO:0008080	N-acetyltransferase activity	IEA	Interproscan
MF	GO:0016407	acetyltransferase activity	None	Extended
MF	GO:0016410	N-acyltransferase activity	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016746	transferase activity, transferring acyl groups	None	Extended
MF	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR001487	Bromodomain	337	418
IPR000182	GNAT_dom	151	226

External Links

No external refs found!

YGR252W

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation