Description : Cytoplasmic thioredoxin isoenzyme; part of thioredoxin system which protects cells against oxidative and reductive stress; forms LMA1 complex with Pbi2p; acts as a cofactor for Tsa1p; required for ER-Golgi transport and vacuole inheritance; with Trx1p, facilitates mitochondrial import of small Tims Tim9p, Tim10p, Tim13p by maintaining them in reduced form; abundance increases under DNA replication stress; TRX2 has a paralog, TRX1, that arose from the whole genome duplication [Source:SGD;Acc:S000003441]
Gene families : OG_03_0000156 (OF) Phylogenetic Tree(s): OG0000156_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YGR209C | |
Cluster | HCCA: Cluster_19 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AOA70364 | No alias | Thioredoxin domain | 0.11 | OF | |
CAG77665 | No alias | Thioredoxin domain | 0.1 | OF | |
CAK43619 | No alias | Thioredoxin | 0.12 | OF | |
CAK44597 | No alias | Thioredoxin | 0.02 | OF | |
CBF90049 | No alias | Thioredoxin | 0.06 | OF | |
EAA33027 | No alias | Thioredoxin domain | 0.11 | OF | |
EAL91479 | No alias | thioredoxin TrxA | 0.07 | OF | |
EAU92470 | No alias | thioredoxin | 0.05 | OF | |
EGR44712 | No alias | Thioredoxin domain | 0.02 | OF | |
ESU07835 | No alias | thioredoxin | 0.05 | OF | |
ESU08169 | No alias | Thioredoxin domain | 0.03 | OF | |
ESU09221 | No alias | Thioredoxin domain | 0.03 | OF | |
ESU17129 | No alias | Thioredoxin domain | 0.02 | OF | |
KHC69768 | No alias | thioredoxin;Thioredoxin | 0.16 | OF | |
KHC75002 | No alias | thioredoxin 1;Thioredoxin | 0.05 | OF | |
MGG_04236T0 | No alias | Thioredoxin [Source:UniProtKB/TrEMBL;Acc:G4NFB7] | 0.03 | OF | |
SPAC7D4.07c.1 | No alias | cytosolic thioredoxin Trx1 [Source:PomBase;Acc:SPAC7D4.07c] | 0.19 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No GO annotation available for this sequence |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR013766 | Thioredoxin_domain | 6 | 101 |
No external refs found! |