Description : Twinfilin; highly conserved actin monomer-sequestering protein involved in regulation of the cortical actin cytoskeleton; coordinates actin filament severing and monomer sequestering at sites of rapid actin turnover; composed of two cofilin-like regions, stimulates actin depolymerization as does the mouse homolog, mTwf1 [Source:SGD;Acc:S000003312]
Gene families : OG_03_0003962 (OF) Phylogenetic Tree(s): OG0003962_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YGR080W | |
Cluster | HCCA: Cluster_46 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
CAG80390 | No alias | Actin-depolymerising factor homology domain | 0.05 | OF | |
CAK38988 | No alias | Cofilin/tropomyosin-type actin-binding protein | 0.09 | OF | |
CBF78688 | No alias | actin monomer binding protein, putative | 0.04 | OF | |
EAL93991 | No alias | actin monomer binding protein, putative | 0.03 | OF | |
EAU88317 | No alias | Actin-depolymerising factor homology domain | 0.01 | OF | |
EGR48525 | No alias | Actin-depolymerising factor homology domain | 0.02 | OF | |
ESU12672 | No alias | Actin-depolymerising factor homology domain | 0.04 | OF | |
SPCC126.06.1 | No alias | twinfilin (predicted) [Source:PomBase;Acc:SPCC126.06] | 0.05 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0003779 | actin binding | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
No external refs found! |