YGL247W

Description : Essential nuclear envelope integral membrane protein; interacts and functions with Apq12p and Brl1p in lipid homeostasis; mutants are defective in nuclear pore complex biogenesis, nuclear envelope morphology, mRNA nuclear export, and are sensitive to sterol biosynthesis inhibitors and membrane fluidizing agents; exhibits synthetic lethal genetic interactions with genes involved in lipid metabolism; homologous to Brl1p [Source:SGD;Acc:S000003216]

Gene families : OG_03_0000986 (OF) Phylogenetic Tree(s): OG0000986_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YGL247W
Cluster	HCCA: Cluster_13

Type	GO Term	Name	Evidence	Source
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0008150	biological_process	None	Extended
CC	GO:0016020	membrane	None	Extended
CC	GO:0031090	organelle membrane	None	Extended
CC	GO:0031965	nuclear membrane	IEA	Interproscan
BP	GO:0042592	homeostatic process	None	Extended
BP	GO:0048878	chemical homeostasis	None	Extended
BP	GO:0055088	lipid homeostasis	IEA	Interproscan
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0065008	regulation of biological quality	None	Extended
CC	GO:0110165	cellular anatomical entity	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR018767	Brl1/Brr6_dom	49	182

External Links

No external refs found!

YGL247W

Expression Profile

Co-expression Networks

Functional Annotation