YGL173C

Description : Evolutionarily-conserved 5'-3' exonuclease; component of cytoplasmic processing (P) bodies involved in mRNA decay; also enters the nucleus and positively regulates transcription initiation and elongation; plays a role in microtubule-mediated processes, filamentous growth, ribosomal RNA maturation, and telomere maintenance; activated by the scavenger decapping enzyme Dcs1p [Source:SGD;Acc:S000003141]

Gene families : OG_03_0002980 (OF) Phylogenetic Tree(s): OG0002980_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YGL173C
Cluster	HCCA: Cluster_8

Target	Alias	Description	ECC score	Gene Family Method
AFR95645	No alias	5'-3' exoribonuclease 1;Xrn1 SH3-like...	0.07	OF
AOA68846	No alias	Exoribonuclease 1, domain 3	0.21	OF
CAG82487	No alias	Putative 5-3 exonuclease	0.04	OF
CBF74062	No alias	exonuclease II	0.02	OF
EAA31689	No alias	Xrn1, D1 domain	0.08	OF
EAL85993	No alias	exonuclease Kem1, putative	0.15	OF
EAU83256	No alias	exonuclease II	0.03	OF
EED79836	No alias	Putative 5-3 exonuclease	0.04	OF
ESU12944	No alias	Putative 5-3 exonuclease	0.04	OF
KHC84072	No alias	5'-3' exoribonuclease 1;Xrn1 SH3-like...	0.23	OF
MGG_12403T0	No alias	5'-3' exoribonuclease 1 [Source:UniProtKB/TrEMBL;Acc:G4MV17]	0.05	OF
POW08118	No alias	Xrn1, helical domain;Putative 5-3 exonuclease	0.03	OF
POW13194	No alias	5'-3' exoribonuclease 1, SH3-like domain;Xrn1, helical...	0.03	OF
SPAC17A5.14.1	No alias	exonuclease II Exo2 [Source:PomBase;Acc:SPAC17A5.14]	0.09	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	IEA	Interproscan
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004518	nuclease activity	None	Extended
MF	GO:0004527	exonuclease activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016788	hydrolase activity, acting on ester bonds	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR041106	XRN1_D2_D3	918	1005
IPR041412	Xrn1_helical	272	680
IPR040992	XRN1_D1	723	914
IPR004859	Put_53exo	1	227
IPR041385	SH3_12	1163	1233
IPR040486	Xrn1_D3	1090	1157

External Links

No external refs found!

YGL173C

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation