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  5. YGL167C

YGL167C


Description : High affinity Ca2+/Mn2+ P-type ATPase; required for Ca2+ and Mn2+ transport into Golgi; involved in Ca2+ dependent protein sorting, processing; D53A mutant (Mn2+ transporting) is rapamycin sensitive, Q783A mutant (Ca2+ transporting) is rapamycin resistant; Mn2+ transport into Golgi lumen required for rapamycin sensitivity; mutations in human homolog ATP2C1 cause acantholytic skin condition Hailey-Hailey disease; human ATP2C1 can complement yeast null mutant [Source:SGD;Acc:S000003135]


Gene families : OG_03_0001687 (OF) Phylogenetic Tree(s): OG0001687_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YGL167C
Cluster HCCA: Cluster_13

Target Alias Description ECC score Gene Family Method Actions
AFR94400 No alias Ca2-transporting ATPase;Cation transporter/ATPase,... 0.03 OF
AOA65811 No alias Cation-transporting P-type ATPase, C-terminal 0.03 OF
CAK48875 No alias secretory pathway Ca2+-ATPase pmrA-Aspergillus niger 0.03 OF
CBF79432 No alias High affinity Ca2+/Mn2+ P-type ATPase 0.02 OF
EAA34982 No alias E1-E2 ATPase 0.03 OF
EAL87677 No alias calcium/mangenease P-type ATPase, putative 0.03 OF
EJF60700 No alias haloacid dehalogenase-like hydrolase 0.03 OF
ESU05697 No alias calcium-transporting ATPase 1 0.04 OF
KHC71728 No alias calcium-transporting P-type ATPase, PMR1-type;"Cation... 0.05 OF

Type GO Term Name Evidence Source

No GO annotation available for this sequence
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Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence
InterPro domains Description Start Stop
IPR004014 ATPase_P-typ_cation-transptr_N 39 108
IPR006068 ATPase_P-typ_cation-transptr_C 762 934
No external refs found!