Description : High affinity Ca2+/Mn2+ P-type ATPase; required for Ca2+ and Mn2+ transport into Golgi; involved in Ca2+ dependent protein sorting, processing; D53A mutant (Mn2+ transporting) is rapamycin sensitive, Q783A mutant (Ca2+ transporting) is rapamycin resistant; Mn2+ transport into Golgi lumen required for rapamycin sensitivity; mutations in human homolog ATP2C1 cause acantholytic skin condition Hailey-Hailey disease; human ATP2C1 can complement yeast null mutant [Source:SGD;Acc:S000003135]
Gene families : OG_03_0001687 (OF) Phylogenetic Tree(s): OG0001687_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YGL167C | |
Cluster | HCCA: Cluster_13 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AFR94400 | No alias | Ca2-transporting ATPase;Cation transporter/ATPase,... | 0.03 | OF | |
AOA65811 | No alias | Cation-transporting P-type ATPase, C-terminal | 0.03 | OF | |
CAK48875 | No alias | secretory pathway Ca2+-ATPase pmrA-Aspergillus niger | 0.03 | OF | |
CBF79432 | No alias | High affinity Ca2+/Mn2+ P-type ATPase | 0.02 | OF | |
EAA34982 | No alias | E1-E2 ATPase | 0.03 | OF | |
EAL87677 | No alias | calcium/mangenease P-type ATPase, putative | 0.03 | OF | |
EJF60700 | No alias | haloacid dehalogenase-like hydrolase | 0.03 | OF | |
ESU05697 | No alias | calcium-transporting ATPase 1 | 0.04 | OF | |
KHC71728 | No alias | calcium-transporting P-type ATPase, PMR1-type;"Cation... | 0.05 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No GO annotation available for this sequence |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
No external refs found! |