Description : Cys-Gly metallo-di-peptidase; forms a complex with Dug2p and Dug3p to degrade glutathione (GSH) and other peptides containing a gamma-glu-X bond in an alternative pathway to GSH degradation by gamma-glutamyl transpeptidase (Ecm38p); human homolog CNDP2 can complement yeast dug1 mutant [Source:SGD;Acc:S000001940]

Gene families : OG_03_0001799 (OF) Phylogenetic Tree(s): OG0001799_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR: YFR044C
Cluster HCCA: Cluster_8

Target Alias Description ECC score Gene Family Method Actions
CAG78363 No alias Peptidase M20, dimerisation domain 0.03 OF
EGR50625 No alias Peptidase M20 0.04 OF
EJF55956 No alias Peptidase dimerisation domain 0.03 OF
KHC75322 No alias Cys-Gly metallodipeptidase DUG1;Peptidase dimerisation... 0.04 OF
MGG_00256T0 No alias Cytosolic non-specific dipeptidase... 0.02 OF
SPBC1198.08.1 No alias dipeptidase Dug1 (predicted) [Source:PomBase;Acc:SPBC1198.08] 0.03 OF

Type GO Term Name Evidence Source
MF GO:0016787 hydrolase activity IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR011650 Peptidase_M20_dimer 225 371
IPR002933 Peptidase_M20 98 473
No external refs found!