Description : Alpha-arrestin involved in ubiquitin-dependent endocytosis; contributes to desensitization of agonist-occupied alpha-factor receptor Ste2p by Rsp5p-independent internalization; PPXY motif-mediated binding of the ubiquitin ligase Rsp5p is not required for adaptation; mutation suppresses the temperature sensitivity of an mck1 rim11 double mutant; SWAT-GFP and mCherry fusion proteins localize to the cytosol; ROG3 has a paralog, ROD1, that arose from the whole genome duplication [Source:SGD;Acc:S000001918]

Gene families : OG_03_0000671 (OF) Phylogenetic Tree(s): OG0000671_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR: YFR022W
Cluster HCCA: Cluster_29

Target Alias Description ECC score Gene Family Method Actions
CAK40614 No alias Arrestin (or S-antigen), C-terminal domain 0.04 OF
CBF74562 No alias CreDPutative uncharacterized protein 0.03 OF
CBF83070 No alias ApyAPutative uncharacterized protein 0.02 OF
EDN99541 No alias Arrestin-like, N-terminal 0.02 OF
SPCC584.15c.1 No alias arrestin involved in ubiquitin-dependent endocytosis... 0.02 OF

Type GO Term Name Evidence Source

No GO annotation available for this sequence

Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR011021 Arrestin-like_N 109 215
IPR011022 Arrestin_C-like 232 393
No external refs found!