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  5. YFR022W

YFR022W


Description : Alpha-arrestin involved in ubiquitin-dependent endocytosis; contributes to desensitization of agonist-occupied alpha-factor receptor Ste2p by Rsp5p-independent internalization; PPXY motif-mediated binding of the ubiquitin ligase Rsp5p is not required for adaptation; mutation suppresses the temperature sensitivity of an mck1 rim11 double mutant; SWAT-GFP and mCherry fusion proteins localize to the cytosol; ROG3 has a paralog, ROD1, that arose from the whole genome duplication [Source:SGD;Acc:S000001918]


Gene families : OG_03_0000671 (OF) Phylogenetic Tree(s): OG0000671_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YFR022W
Cluster HCCA: Cluster_29

Target Alias Description ECC score Gene Family Method Actions
CAK40614 No alias Arrestin (or S-antigen), C-terminal domain 0.04 OF
CBF74562 No alias CreDPutative uncharacterized protein 0.03 OF
CBF83070 No alias ApyAPutative uncharacterized protein 0.02 OF
EDN99541 No alias Arrestin-like, N-terminal 0.02 OF
SPCC584.15c.1 No alias arrestin involved in ubiquitin-dependent endocytosis... 0.02 OF

Type GO Term Name Evidence Source

No GO annotation available for this sequence
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Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence
InterPro domains Description Start Stop
IPR011021 Arrestin-like_N 109 215
IPR011022 Arrestin_C-like 232 393
No external refs found!