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  5. YFR021W

YFR021W


Description : Phosphoinositide binding protein; required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; binds both phosphatidylinositol (3,5)-bisphosphate and phosphatidylinositol 3-phosphate; WD-40 repeat protein; relocalizes from vacuole to cytoplasm upon DNA replication stress; has 4 mammalian homologs WIPI1, WIPI2, WIPI3 and WIPI4/WDR45; mutations in human WDR45 cause static encephalopathy of childhood with neurodegeneration in adulthood [Source:SGD;Acc:S000001917]


Gene families : OG_03_0001019 (OF) Phylogenetic Tree(s): OG0001019_tree

Sequence : coding (download), protein (download)


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Type Description Actions
Neighborhood HRR: YFR021W
Cluster HCCA: Cluster_23

Target Alias Description ECC score Gene Family Method Actions
KHC82834 No alias hypothetical protein;"WD domain, G-beta repeat" 0.03 OF
KHC83114 No alias hypothetical protein 0.02 OF

Type GO Term Name Evidence Source
MF GO:0005515 protein binding IEA Interproscan
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Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence
InterPro domains Description Start Stop
IPR001680 WD40_repeat 236 269
IPR001680 WD40_repeat 287 317
No external refs found!