Description : Regulatory subunit of protein phosphatase PP4; presence of Psy4p in the PP4 complex (along with catalytic subunit Pph3p and Psy2p) is required for dephosphorylation of the histone variant H2AX, but not for dephosphorylation of Rad53p, during recovery from the DNA damage checkpoint; localization is cell-cycle dependent and regulated by Cdc28p phosphorylation; required for cisplatin resistance; homolog of mammalian R2 [Source:SGD;Acc:S000000142]
Gene families : OG_03_0004563 (OF) Phylogenetic Tree(s): OG0004563_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YBL046W | |
Cluster | HCCA: Cluster_5 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
EDO03834 | No alias | Protein phosphatase 4 core regulatory subunit R2 | 0.02 | OF | |
EGR47463 | No alias | Protein phosphatase 4 core regulatory subunit R2 | 0.02 | OF | |
ESU05914 | No alias | hypothetical protein | 0.02 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0019888 | protein phosphatase regulator activity | IEA | Interproscan |
CC | GO:0030289 | protein phosphatase 4 complex | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR015267 | PPP4R2 | 3 | 298 |
No external refs found! |