Description : Proteasome activator; binds the core proteasome (CP) and stimulates proteasome-mediated protein degradation by inducing gate opening; required for sequestering CP into proteasome storage granule (PSG) during quiescent phase and for nuclear import of CP in proliferating cells; required for resistance to bleomycin, may be involved in protecting against oxidative damage; similar to mammalian PA200 [Source:SGD;Acc:S000001887]
Gene families : OG_03_0001992 (OF) Phylogenetic Tree(s): OG0001992_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YFL007W | |
Cluster | HCCA: Cluster_33 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AFR96298 | No alias | proteasome activator subunit 4;Proteasome-substrate-size... | 0.13 | OF | |
AOA69364 | No alias | Proteasome activator Blm10, N-terminal | 0.12 | OF | |
CAG81353 | No alias | Proteasome activator Blm10, N-terminal | 0.09 | OF | |
CAK38794 | No alias | Domain of unknown function (DUF3437) | 0.02 | OF | |
EAL89662 | No alias | proteasome activator subunit 4, putative | 0.12 | OF | |
EDN90755 | No alias | Proteasome activator Blm10, N-terminal | 0.09 | OF | |
EFI28574 | No alias | Proteasome activator complex subunit 4 C-terminal... | 0.06 | OF | |
EFI28576 | No alias | membrane protein | 0.03 | OF | |
EGR45261 | No alias | Proteasome activator Blm10, N-terminal | 0.04 | OF | |
ESA42166 | No alias | Proteasome activator Blm10, N-terminal | 0.07 | OF | |
ESA42167 | No alias | Proteasome activator Blm10, N-terminal | 0.07 | OF | |
ESU12505 | No alias | Proteasome activator Blm10, mid region | 0.12 | OF | |
KHC81832 | No alias | proteasome activator subunit... | 0.15 | OF | |
POV98026 | No alias | Proteasome activator Blm10, mid region | 0.02 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No GO annotation available for this sequence |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
No external refs found! |