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  5. YBL024W

YBL024W


Description : S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase; methylates cytosine to m5C at several positions in tRNAs and intron-containing pre-tRNAs; increases proportion of tRNALeu(CAA) with m5C at wobble position in response to hydrogen peroxide, causing selective translation of mRNA from genes enriched in TTG codon; loss of NCL1 confers hypersensitivity to oxidative stress; similar to Nop2p and human proliferation associated nucleolar protein p120 [Source:SGD;Acc:S000000120]


Gene families : OG_03_0001716 (OF) Phylogenetic Tree(s): OG0001716_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YBL024W
Cluster HCCA: Cluster_16

Target Alias Description ECC score Gene Family Method Actions
AFR95255 No alias multisite-specific... 0.28 OF
AOA70140 No alias SAM-dependent methyltransferase RsmB/NOP2-type 0.18 OF
CAG79223 No alias SAM-dependent methyltransferase RsmB/NOP2-type 0.37 OF
CAK44117 No alias 16S rRNA methyltransferase RsmB/F 0.09 OF
CBF88845 No alias methyltransferase 0.2 OF
EAA32836 No alias SAM-dependent methyltransferase RsmB/NOP2-type 0.19 OF
EAL90750 No alias methyltransferase (Ncl1), putative 0.26 OF
EAU81513 No alias tRNA (cytosine-5-)-methyltransferase 0.15 OF
EDO00148 No alias SAM-dependent methyltransferase RsmB/NOP2-type 0.07 OF
EED54457 No alias methyltransferase (Ncl1), putative 0.04 OF
EGR51707 No alias SAM-dependent methyltransferase RsmB/NOP2-type 0.06 OF
EJF61835 No alias 16S rRNA methyltransferase RsmB/F 0.05 OF
ESU16367 No alias SAM-dependent methyltransferase RsmB/NOP2-type 0.19 OF
KHC71376 No alias multisite-specific tRNA... 0.36 OF
MGG_13217T0 No alias tRNA (Cytosine-5-)-methyltransferase NCL1... 0.18 OF
POV94461 No alias SAM-dependent methyltransferase RsmB/NOP2-type 0.06 OF
SPAC17D4.04.1 No alias tRNA (cytosine-5-)-methyltransferase (predicted)... 0.04 OF
SPAC23C4.17.1 No alias tRNA (cytosine-5-)-methyltransferase (predicted)... 0.2 OF

Type GO Term Name Evidence Source
MF GO:0008168 methyltransferase activity IEA Interproscan
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Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence
InterPro domains Description Start Stop
IPR001678 MeTrfase_RsmB/NOP2 159 408
No external refs found!