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  5. YDR533C

YDR533C


Description : Methylglyoxalase that converts methylglyoxal to D-lactate; involved in oxidative stress resistance, diauxic shift, and stationary phase survival; has similarity to E. coli Hsp31 and C. albicans Glx3p; member of the DJ-1/ThiJ/PfpI superfamily, which includes human DJ-1 involved in Parkinson's disease and cancer; exists as a dimer and contains a putative metal-binding site; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000002941]


Gene families : OG_03_0000470 (OF) Phylogenetic Tree(s): OG0000470_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YDR533C
Cluster HCCA: Cluster_19

Target Alias Description ECC score Gene Family Method Actions
AFR97890 No alias hypothetical protein;DJ-1/PfpI family 0.05 OF
CAG77632 No alias DJ-1/PfpI 0.03 OF
CAK46205 No alias DJ-1/PfpI family 0.05 OF
EAA33109 No alias DJ-1/PfpI 0.06 OF
EAL86161 No alias ThiJ/PfpI family protein 0.02 OF
EAU84741 No alias ThiJ/PfpI 0.04 OF
ESU15485 No alias DJ-1/PfpI 0.03 OF
KHC78815 No alias hypothetical protein;DJ-1/PfpI family 0.06 OF
SPAC11D3.13.1 No alias ThiJ domain protein [Source:PomBase;Acc:SPAC11D3.13] 0.06 OF
SPBC947.09.1 No alias ThiJ domain protein [Source:PomBase;Acc:SPBC947.09] 0.05 OF
SPCC757.03c.1 No alias glyoxylase III Hsp3101 [Source:PomBase;Acc:SPCC757.03c] 0.03 OF

Type GO Term Name Evidence Source

No GO annotation available for this sequence
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Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence
InterPro domains Description Start Stop
IPR002818 DJ-1/PfpI 29 224
No external refs found!