YDR519W


Description : Membrane-bound peptidyl-prolyl cis-trans isomerase (PPIase); binds to the drugs FK506 and rapamycin; expression pattern suggests possible involvement in ER protein trafficking; relocalizes from nucleus to vacuole upon DNA replication stress; mutation is functionally complemented by human FKBP2 [Source:SGD;Acc:S000002927]


Gene families : OG_03_0000280 (OF) Phylogenetic Tree(s): OG0000280_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YDR519W
Cluster HCCA: Cluster_30

Target Alias Description ECC score Gene Family Method Actions
AOA67139 No alias FKBP-type peptidyl-prolyl cis-trans isomerase domain 0.02 OF
CAG84187 No alias FKBP-type peptidyl-prolyl cis-trans isomerase domain 0.03 OF
CAK43162 No alias FKBP-type peptidyl-prolyl cis-trans isomerase 0.02 OF
CAK43786 No alias FKBP-type peptidyl-prolyl cis-trans isomerase 0.07 OF
CBF80348 No alias FK506-binding protein 2 Precursor 0.09 OF
EAA30274 No alias FKBP-type peptidyl-prolyl cis-trans isomerase domain 0.03 OF
EAL89058 No alias FKBP-type peptidyl-prolyl isomerase, putative 0.03 OF
EAU90964 No alias FKBP-type peptidyl-prolyl cis-trans isomerase domain 0.03 OF
EED78748 No alias FKBP-type peptidyl-prolyl cis-trans isomerase domain 0.02 OF
EGR48235 No alias FKBP-type peptidyl-prolyl cis-trans isomerase domain 0.07 OF
MGG_07234T0 No alias FK506-binding protein 2 [Source:UniProtKB/TrEMBL;Acc:G4MU46] 0.02 OF
SPBC839.17c.1 No alias FKBP12 peptidyl-prolyl cis-trans isomerase Fkh1... 0.02 OF

Type GO Term Name Evidence Source
MF GO:0003755 peptidyl-prolyl cis-trans isomerase activity IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR001179 PPIase_FKBP_dom 39 129
No external refs found!