Description : Cytoplasmic glutaredoxin; thioltransferase, glutathione-dependent disulfide oxidoreductase involved in maintaining redox state of target proteins, also exhibits glutathione peroxidase activity, expression induced in response to stress; GRX2 has two in-frame start codons resulting in a shorter isoform that is retained in the cytosol and a longer form translocated to the mitochondrial matrix; GRX2 has a paralog, GRX1, that arose from the whole genome duplication [Source:SGD;Acc:S000002921]
Gene families : OG_03_0000265 (OF) Phylogenetic Tree(s): OG0000265_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
| Type | Description | Actions |
|---|---|---|
| Neighborhood | HRR: YDR513W | |
| Cluster | HCCA: Cluster_64 |
| Target | Alias | Description | ECC score | Gene Family Method | Actions |
|---|---|---|---|---|---|
| CAG81775 | No alias | Glutaredoxin | 0.05 | OF | |
| CAK43281 | No alias | Glutaredoxin | 0.01 | OF | |
| EAA32349 | No alias | Glutaredoxin | 0.03 | OF | |
| EAL88321 | No alias | glutaredoxin Grx1, putative | 0.04 | OF | |
| EAL90238 | No alias | Glutaredoxin domain protein | 0.02 | OF | |
| EAU92516 | No alias | Glutaredoxin | 0.02 | OF | |
| ESU07487 | No alias | Glutaredoxin | 0.03 | OF | |
| KHC82840 | No alias | glutaredoxin;Glutaredoxin | 0.08 | OF | |
| SPAC4F10.20.1 | No alias | glutaredoxin Grx1 [Source:PomBase;Acc:SPAC4F10.20] | 0.05 | OF |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
| MF | GO:0009055 | electron transfer activity | IEA | Interproscan |
| MF | GO:0015035 | protein disulfide oxidoreductase activity | IEA | Interproscan |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
No Predicted GO terms available for this sequence |
| InterPro domains | Description | Start | Stop |
|---|---|---|---|
| IPR002109 | Glutaredoxin | 53 | 119 |
| No external refs found! |