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  5. YDR457W

YDR457W


Description : E3 ubiquitin ligase of the hect-domain class; has a role in mRNA export from the nucleus and may regulate transcriptional coactivators; involved in degradation of excess histones; interacts with Dia2p and is required for Dia2p degradation; required to target Cdc6p for ubiquitin-mediated destruction during G1 phase [Source:SGD;Acc:S000002865]


Gene families : OG_03_0001964 (OF) Phylogenetic Tree(s): OG0001964_tree

Sequence : coding (download), protein (download)


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Type Description Actions
Neighborhood HRR: YDR457W
Cluster HCCA: Cluster_12

Target Alias Description ECC score Gene Family Method Actions
AFR97151 No alias E3 ubiquitin-protein ligase HUWE1;HECT-domain... 0.12 OF
AOA69338 No alias HECT domain 0.12 OF
CAG82782 No alias E3 ubiquitin ligase, domain of unknown function DUF913 0.07 OF
CAK38851 No alias Ubiquitin binding region 0.09 OF
CBF85910 No alias ubiquitin-protein ligase 0.09 OF
EAA34194 No alias E3 ubiquitin ligase, domain of unknown function DUF908 0.07 OF
EAL89711 No alias ubiquitin-protein ligase (Tom1), putative 0.2 OF
EAU91398 No alias Huwe1 protein 0.14 OF
EGR50706 No alias HECT domain 0.1 OF
EJF60455 No alias Domain of Unknown Function (DUF908) 0.09 OF
ESU05840 No alias HECT domain 0.13 OF
KHC81379 No alias E3 ubiquitin-protein ligase HUWE1;Domain of Unknown... 0.31 OF
POW08213 No alias E3 ubiquitin ligase, domain of unknown function... 0.04 OF
POW08214 No alias HECT domain;Ubiquitin-associated domain;HUWE1/Rev1,... 0.08 OF
SPAC19D5.04.1 No alias HECT-type ubiquitin ligase E3 Ptr1... 0.2 OF

Type GO Term Name Evidence Source
MF GO:0004842 ubiquitin-protein transferase activity IEA Interproscan
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Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence
InterPro domains Description Start Stop
IPR025527 HUWE1/Rev1_UBM 2328 2359
IPR025527 HUWE1/Rev1_UBM 2372 2399
IPR010314 E3_Ub_ligase_DUF913 448 691
IPR000569 HECT_dom 2963 3267
IPR010309 E3_Ub_ligase_DUF908 93 386
No external refs found!