Description : Na+/H+ and K+/H+ exchanger; required for intracellular sequestration of Na+ and K+; located in the vacuole and late endosome compartments; required for osmotolerance to acute hypertonic shock and for vacuolar fusion; ortholog of human NHE9, which is linked to autism [Source:SGD;Acc:S000002864]

Gene families : OG_03_0002375 (OF) Phylogenetic Tree(s): OG0002375_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR: YDR456W
Cluster HCCA: Cluster_34

Target Alias Description ECC score Gene Family Method Actions
CAG77702 No alias Cation/H+ exchanger 0.02 OF
EJF60172 No alias Sodium/hydrogen exchanger family 0.02 OF
ESU11482 No alias Cation/H+ exchanger 0.02 OF
MGG_06437T0 No alias Sodium/hydrogen exchanger 3 [Source:UniProtKB/TrEMBL;Acc:G4N7A3] 0.04 OF
POW14768 No alias Cation/H+ exchanger 0.02 OF
SPAC15A10.06.1 No alias CPA1 sodium ion/proton antiporter (predicted)... 0.05 OF

Type GO Term Name Evidence Source
BP GO:0006812 cation transport IEA Interproscan
MF GO:0015299 solute:proton antiporter activity IEA Interproscan
CC GO:0016021 integral component of membrane IEA Interproscan
BP GO:0055085 transmembrane transport IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR006153 Cation/H_exchanger 69 484
No external refs found!