Description : SUMO E3 ligase; promotes attachment of small ubiquitin-related modifier sumo (Smt3p) to primarily cytoplasmic proteins; regulates Rsp5p ubiquitin ligase activity and is in turn itself regulated by Rsp5p; required for sumoylation of septins and histone H3 variant Cse4p, a prerequisite for STUbL-mediated Ub-dependent degradation; localizes to the septin ring; acts as an adapter between E2, Ubc9p and substrates; tends to compensate for survival of DNA damage in absence of Nfi1p [Source:SGD;Acc:S000002817]

Gene families : OG_03_0002246 (OF) Phylogenetic Tree(s): OG0002246_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR: YDR409W
Cluster HCCA: Cluster_18

Target Alias Description ECC score Gene Family Method Actions
AOA68557 No alias SAP domain 0.02 OF
CAG79904 No alias SAP domain 0.04 OF
CBF70854 No alias SUMO ligase SizA, putative 0.02 OF
EAL85515 No alias SUMO ligase SizA, putative 0.02 OF
KHC82942 No alias E3 SUMO-protein ligase PIAS1;PINIT domain;MIZ/SP-RING... 0.02 OF
MGG_08837T0 No alias MIZ zinc finger protein [Source:UniProtKB/TrEMBL;Acc:G4MV34] 0.01 OF
SPAC1687.05.1 No alias SUMO E3 ligase Pli1 [Source:PomBase;Acc:SPAC1687.05] 0.02 OF

Type GO Term Name Evidence Source
MF GO:0008270 zinc ion binding IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR023321 PINIT 175 312
IPR004181 Znf_MIZ 357 405
IPR003034 SAP_dom 35 68
No external refs found!