YDR385W

Description : Elongation factor 2 (EF-2), also encoded by EFT1; catalyzes ribosomal translocation during protein synthesis; contains diphthamide, the unique posttranslationally modified histidine residue specifically ADP-ribosylated by diphtheria toxin; EFT2 has a paralog, EFT1, that arose from the whole genome duplication [Source:SGD;Acc:S000002793]

Gene families : OG_03_0000282 (OF) Phylogenetic Tree(s): OG0000282_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YDR385W
Cluster	HCCA: Cluster_8

Target	Alias	Description	ECC score	Gene Family Method
AFR94637	No alias	elongation factor 2;Elongation factor G...	0.12	OF
AFR95055	No alias	U5 small nuclear ribonucleoprotein component;Elongation...	0.02	OF
AOA67359	No alias	Elongation Factor G, domain II	0.11	OF
CAG83532	No alias	Transcription factor, GTP-binding domain	0.17	OF
CBF69688	No alias	elongation factor 2	0.05	OF
EAA33050	No alias	Transcription factor, GTP-binding domain	0.06	OF
EAL93648	No alias	translation elongation factor EF-2 subunit, putative	0.09	OF
EAU92297	No alias	Elongation factor EFG, domain V-likeTranscription...	0.06	OF
EDN96415	No alias	Elongation factor EFG, domain V-like	0.08	OF
EGR52062	No alias	Elongation factor EFG, domain V-like	0.09	OF
ESU16179	No alias	elongation factor 2	0.07	OF
KHC81371	No alias	elongation factor 2;"Elongation Factor G, domain...	0.21	OF
MGG_01742T0	No alias	Elongation factor 2 [Source:UniProtKB/TrEMBL;Acc:G4MVB0]	0.11	OF
POW07285	No alias	Translation elongation factor EFG/EF2, domain...	0.11	OF
POW17228	No alias	Transcription factor, GTP-binding domain;Translation...	0.04	OF
SPAC513.01c.1	No alias	translation elongation factor 2 (EF-2) Eft2,A...	0.17	OF
SPCP31B10.07.1	No alias	translation elongation factor 2 (EF-2) Eft2,B...	0.2	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0001882	nucleoside binding	None	Extended
MF	GO:0001883	purine nucleoside binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003924	GTPase activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
MF	GO:0005525	GTP binding	IEA	Interproscan
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
MF	GO:0019001	guanyl nucleotide binding	None	Extended
MF	GO:0032549	ribonucleoside binding	None	Extended
MF	GO:0032550	purine ribonucleoside binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032561	guanyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR004161	EFTu-like_2	394	470
IPR041095	EFG_II	486	548
IPR000640	EFG_V-like	724	809
IPR005517	Transl_elong_EFG/EF2_IV	609	720
IPR000795	TF_GTP-bd_dom	18	344

External Links

No external refs found!

YDR385W

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation