YDR375C

Description : Protein translocase and chaperone required for Complex III assembly; member of the AAA ATPase family; forms a homo-oligomeric complex in the mitochondrial inner membrane that translocates the C-terminal domain of Rip1p from the matrix across the inner membrane and delivers it to an assembly intermediate of respiratory Complex III; also required for assembly of the Qcr10p subunit; mutation is functionally complemented by human homolog BCS1L, linked to neonatal diseases [Source:SGD;Acc:S000002783]

Gene families : OG_03_0000154 (OF) Phylogenetic Tree(s): OG0000154_tree

Sequence : coding (download), protein (download)

Download

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YDR375C
Cluster	HCCA: Cluster_27

Target	Alias	Description	ECC score	Gene Family Method
AFR93900	No alias	mitochondrial chaperone BCS1;BCS1 N terminal;ATPase...	0.03	OF
CAG80554	No alias	ATPase, AAA-type, core	0.03	OF
CBF83347	No alias	mitochondrial chaperone BCS1, putative	0.03	OF
EAA36095	No alias	ATPase, AAA-type, core	0.1	OF
EAL92283	No alias	mitochondrial chaperone BCS1, putative	0.02	OF
EAU88808	No alias	mitochondrial chaperone BCS1	0.07	OF
EDN96306	No alias	ATPase, AAA-type, core	0.01	OF
EED54827	No alias	mitochondrial chaperone BCS1, putative	0.03	OF
EGR45251	No alias	BCS1, N-terminal	0.03	OF
ESU07620	No alias	BCS1, N-terminal	0.04	OF
ESU08251	No alias	ATPase, AAA-type, core	0.05	OF
KHC70463	No alias	mitochondrial chaperone BCS1;ATPase family associated...	0.16	OF
POW05952	No alias	ATPase, AAA-type, core;BCS1, N-terminal	0.02	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
BP	GO:0017004	cytochrome complex assembly	None	Extended
BP	GO:0017062	respiratory chain complex III assembly	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
BP	GO:0022607	cellular component assembly	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0033108	mitochondrial respiratory chain complex assembly	None	Extended
BP	GO:0034551	mitochondrial respiratory chain complex III assembly	IEA	Interproscan
BP	GO:0034622	cellular protein-containing complex assembly	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043933	protein-containing complex subunit organization	None	Extended
BP	GO:0065003	protein-containing complex assembly	None	Extended
BP	GO:0071840	cellular component organization or biogenesis	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

Toggle parental

Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR014851	BCS1_N	61	228
IPR003959	ATPase_AAA_core	264	387

External Links

No external refs found!

YDR375C

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation