Description : Component of cytosolic iron-sulfur protein assembly (CIA) machinery; acts at late step of Fe-S cluster assembly; forms CIA targeting complex with Cia2p and Met18p that directs Fe-S cluster incorporation into subset of proteins involved in methionine biosynthesis, DNA replication and repair, transcription, telomere maintenance; contains WD40 repeats; human homolog CIAO1 can complement yeast cia1 null mutant [Source:SGD;Acc:S000002675]

Gene families : OG_03_0003755 (OF) Phylogenetic Tree(s): OG0003755_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR: YDR267C
Cluster HCCA: Cluster_58

Target Alias Description ECC score Gene Family Method Actions
AFR97315 No alias WD40 repeat protein Ciao1;WD domain, G-beta repeat 0.02 OF
EAA34013 No alias WD40 repeat 0.04 OF
EGR46696 No alias WD40 repeat 0.03 OF
ESU08812 No alias WD40 repeat 0.02 OF
KHC75173 No alias hypothetical protein;"WD domain, G-beta repeat" 0.03 OF
MGG_03150T0 No alias Cytosolic iron-sulfur protein assembly protein 1... 0.06 OF

Type GO Term Name Evidence Source
MF GO:0005515 protein binding IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR001680 WD40_repeat 55 85
IPR001680 WD40_repeat 144 181
IPR001680 WD40_repeat 187 227
IPR001680 WD40_repeat 99 134
No external refs found!