YDR190C

Description : ATP-dependent DNA helicase, also known as pontin; member of the AAA+ and RuvB-like protein families; similar to Rvb2p; conserved component of multiple complexes including the INO80 complex, the Swr1 complex, and the R2TP complex (Rvb1-Rvb2-Tah1-Pih1); involved in multiple processes such as chromatin remodeling, box C/D snoRNP assembly, and RNA polymerase II assembly [Source:SGD;Acc:S000002598]

Gene families : OG_03_0002531 (OF) Phylogenetic Tree(s): OG0002531_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YDR190C
Cluster	HCCA: Cluster_13

Target	Alias	Description	ECC score	Gene Family Method
AFR92245	No alias	RuvB-like helicase 1;TIP49 AAA-lid domain;TIP49 P-loop domain	0.03	OF
AOA69733	No alias	RuvB-like, AAA-lid domain	0.03	OF
CAG82430	No alias	RuvB-like, AAA-lid domain	0.03	OF
CAK38857	No alias	TIP49 P-loop domain	0.05	OF
EAA26533	No alias	TIP49, P-loop domain	0.02	OF
EAL89716	No alias	AAA family ATPase Pontin, putative	0.04	OF
EDO02864	No alias	TIP49, P-loop domain	0.03	OF
EGR52325	No alias	TIP49, P-loop domain	0.02	OF
ESU11077	No alias	RuvB-like, AAA-lid domain	0.03	OF
KHC76751	No alias	RuvB-like helicase 1;TIP49 P-loop domain;TIP49 AAA-lid domain	0.04	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003678	DNA helicase activity	IEA	Interproscan
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004386	helicase activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
MF	GO:0008094	DNA-dependent ATPase activity	None	Extended
MF	GO:0008144	drug binding	None	Extended
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0016887	ATPase activity	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR010339	TIP49_P-loop	23	377
IPR041048	RuvB-like_C	383	448

External Links

No external refs found!

YDR190C

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation