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  5. YDR129C

YDR129C


Description : Fimbrin, actin-bundling protein; cooperates with Scp1p in organization and maintenance of the actin cytoskeleton; phosphorylated by Cdc28p/Clb2p in metaphase on T103, to regulate conformation, and modulate actin filament binding affinity and actin cable dynamics; relocalizes from the plasma membrane to the cytoplasm upon DNA replication stress; human homologs PLS3 and LCP1 implicated in spinocerebellar ataxia type 2 (SCA2) can each complement yeast null mutant [Source:SGD;Acc:S000002536]


Gene families : OG_03_0004010 (OF) Phylogenetic Tree(s): OG0004010_tree

Sequence : coding (download), protein (download)


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Type Description Actions
Neighborhood HRR: YDR129C
Cluster HCCA: Cluster_65

Target Alias Description ECC score Gene Family Method Actions
AFR97481 No alias fimbrin;Calponin homology (CH) domain 0.03 OF
EAA27341 No alias Calponin homology domain 0.05 OF
EAL93040 No alias actin-bundling protein Sac6, putative 0.02 OF
KHC73437 No alias fimbrin;Calponin homology (CH) domain 0.03 OF
SPBC1778.06c.1 No alias fimbrin [Source:PomBase;Acc:SPBC1778.06c] 0.02 OF

Type GO Term Name Evidence Source
MF GO:0005515 protein binding IEA Interproscan
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Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence
InterPro domains Description Start Stop
IPR001715 CH-domain 140 257
IPR001715 CH-domain 537 640
IPR001715 CH-domain 413 520
IPR001715 CH-domain 288 390
No external refs found!